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Originally from Dublin, Moira O'Deorain made waves in the scientific community more than a decade prior to the game, after publishing a controversial paper detailing a methodology for creating custom genetic programs that could alter DNA at a cellular level. Most scientists found her research dangerous due to its perceived ethical shortfalls, with some even going so far as to accuse her of having the same obsession with scientific advancement that started the Omnic Crisis. Adding to the controversy, other geneticists were unable to reproduce the results of her research. With her career stalled, Moira received a lifeline from an unlikely source: Blackwatch, the covert ops division of Overwatch under the command of Gabriel Reyes. Her involvement with Blackwatch was kept a secret until inquiries following an incident in Venice revealed her work, forcing Overwatch to publicly disavow any ties to her or her work. After Overwatch disbanded, Moira was employed by the Ministries, the scientific collective that founded the city of Oasis in southern Iraq, as the head of the Ministry of Genetics. She was also financed by Talon, and (along with Doomfist and Reaper) is among the members of its ruling council who appear in the game. Her origin story video reveals that she is responsible for transforming Gabriel Reyes into Reaper. She had made an appearance in Doomfist's introductory comic, released earlier in 2017.